Nucleic acid modified superparamagnetic photonic crystal sensing material, preparation method and application

The invention provides a nucleic acid modified superparamagnetic photonic crystal sensing material as well as a preparation method and application thereof. The preparation method comprises the following steps: step 1, preparing magnetic nanoparticles by utilizing a chemical high-temperature hydrothe...

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Hauptverfasser: GU ZHIJIA, PU YONGFU, LI MAOKANG, YAO LIHUA, EIWA, YANG YING, HONG XIAODI, DAI ZHIGANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a nucleic acid modified superparamagnetic photonic crystal sensing material as well as a preparation method and application thereof. The preparation method comprises the following steps: step 1, preparing magnetic nanoparticles by utilizing a chemical high-temperature hydrothermal method; step 2, coating a layer of SiO2 outside the magnetic nano-microsphere by using a method to prepare a superparamagnetic nano-microsphere with a core-shell structure; 3, amino group modification is carried out on the surfaces of the superparamagnetic nano microspheres; 4, a nucleic acid DNA probe capable of recognizing heavy metal is adsorbed through the electrostatic adsorption effect between amino and DNA, and nucleic acid modified superparamagnetic nanometer microspheres are prepared; and 5, the nucleic acid modified superparamagnetic photonic crystal sensing material is prepared. The problem that large substances such as nucleic acid are modified by a traditional-configuration photonic crystal materi