Application of GHRH-A in preparation of medicine for preventing and treating senile deafness and composition
The invention relates to the technical field of biomedicine, and discloses an application of GHRH-A in preparation of a medicine for preventing and treating senile deafness, and the technical key points are as follows: the GHRH-A is MR409; the medicine mainly takes an injection as an administration...
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Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to the technical field of biomedicine, and discloses an application of GHRH-A in preparation of a medicine for preventing and treating senile deafness, and the technical key points are as follows: the GHRH-A is MR409; the medicine mainly takes an injection as an administration dosage form; the dosage of the effective component MR409 in the medicine is 10 [mu] g; the concentration of the effective component MR409 in the medicine is 1 mu M. The MR-409 can obviously improve hearing function impairment caused by senile deafness, reduce the hair cell deletion rate and improve banding synapse loss of inner hair cells of senile deafness mice, and the mechanism of the MR-409 may be related to reduction of cochlea hair cell apoptosis. The new application of the MR-409 provides a new strategy for the treatment of the senile deafness, and has important clinical treatment significance.
本发明涉及生物医学技术领域,且公开了一种GHRH-A在制备防治老年性耳聋药物中的应用,其技术要点是:所述GHRH-A为MR409;所述药物主要以注射剂作为给药剂型;所述药物中有效成分MR409的剂量为10μg;所述药物中有效成分M |
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