Compound oil solution preparation for long-acting analgesia and preparation method thereof

The invention discloses a compound oil solution preparation for long-acting analgesia, the preparation comprises ropivacaine or salt thereof, dexamethasone or ester thereof, phospholipid, ethanol and oil for injection, the concentration of ropivacaine is 1.0-5.0% (w/w) in terms of ropivacaine, and the concentration of dexamethasone or ester thereof is 0.005-0.5% (w/w) in terms of dexamethasone. The invention provides the long-acting analgesic compound preparation which is simple in preparation process, low in cost and convenient for industrial production. 本发明公开了一种长效镇痛用复方油溶液制剂，所述制剂包括罗哌卡因或其盐、地塞米松或其酯、磷脂、乙醇和注射用油，以罗哌卡因计所述罗哌卡因的浓度为1.0～5.0％(w/w)，以地塞米松计所述地塞米松或其酯的浓度为0.005～0.5％(w/w)。本发明提供了一种制备工艺简单、成本低、便于工业化生产的长效镇痛复方制剂。