Biological indicator with test microorganisms encapsulated by wax composition

The invention provides an integral matching type sterilization process biological indicator. The indicator includes a housing. A test microorganism disposed in the housing is encapsulated by a wax composition. The wax composition comprises a long-chain (greater than C22) linear or branched alkyl or alkenyl alcohol wherein the alkyl or alkenyl alcohol is not linked to a short-chain alkyl or aryl (C1-C6) group via an ester or ether linkage wherein the alkyl or alkenyl alcohol is not linked to a long-chain (C8-C36) alkyl or alkenyl group via an ester or ether linkage, wherein the alkyl or alkenyl alcohol is not linked to a linear or branched long-chain (C8-C36) alkyl or alkenyl amine or acid via an amide bond. The melting point of the wax composition is between 78 DEG C and 120 DEG C. The housing also contains a nutritional composition and an openable container containing a liquid medium. 本发明提供了一种整装配套式灭菌过程生物指示器。所述指示器包括壳体。设置在所述壳体中的测试微生物由蜡组合物包封。所述蜡组合物包含长链(大于C22)直链或支链烷基或烯基醇，其中所述烷基或烯基醇不通过酯键或醚键连接到短链烷基或芳基(C1-C6)基团，其中所