FXIa inhibitor compound impurity as well as preparation method and application thereof

FXIa inhibitor compound impurity as well as preparation method and application thereof

The invention discloses FXIa inhibitor compound impurities and a preparation method and application thereof, the FXIa inhibitor compound impurities comprise an FXIa inhibitor compound impurity 1, an FXIa inhibitor compound impurity 2 and an FXIa inhibitor compound impurity 4, the invention further d...

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Bibliographische Detailangaben
Hauptverfasser: HUA HUAIJIE, CHEN SHUJUN, LIAN XIAOLEI, LI QINZE, XU WENJIE, CHEN XIANGMENG
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention discloses FXIa inhibitor compound impurities and a preparation method and application thereof, the FXIa inhibitor compound impurities comprise an FXIa inhibitor compound impurity 1, an FXIa inhibitor compound impurity 2 and an FXIa inhibitor compound impurity 4, the invention further discloses the preparation method and application of the impurities, and the FXIa inhibitor compound related impurities and the preparation method thereof provide a basis for quality research of FXIa inhibitor compound bulk drugs and pharmaceutical compositions thereof. FXIa抑制剂化合物杂质及其制备方法和用途，包括FXIa抑制剂化合物杂质1、杂质2、杂质4，还公开了杂质的制备方法和用途，提供的FXIa抑制剂化合物相关杂质及其制备方法为FXIa抑制剂化合物原料药及其药物组合物的质量研究提供了基础。