Pyridopyrimidone derivative and application of pyridopyrimidone derivative as aromatic hydrocarbon receptor modulator

The present invention relates to a novel compound effective as a modulator of aromatic hydrocarbon receptor (AhR), a pharmaceutical composition comprising the compound as an active ingredient for modulating AhR, or preventing or treating diseases, disorders or conditions associated with AhR activity...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LI BAOLING, JOO MIN-SUNG, DOH HYUN-MI, KANG JI-HEE, LEE EUN-HYE, LEE WON HYUNG, PARK GA-YOUNG, KIM SOONG-HYUN, PARK JUNG-SANG, SUNG HYUN-JUNG, PARK YU-JIN, CHOI YOU-JUNG, SONG MIN-SU, GAO ENBI, CHA DAE-WON, KIM YOON-JUNG, YOON TAE-YOUNG, BAE SE-RI
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to a novel compound effective as a modulator of aromatic hydrocarbon receptor (AhR), a pharmaceutical composition comprising the compound as an active ingredient for modulating AhR, or preventing or treating diseases, disorders or conditions associated with AhR activity, and thus can be used as a medicament for preventing or treating diseases, disorders or conditions associated with AhR activity, and for preventing or treating diseases, disorders or conditions associated with AhR activity. , especially cancer, cancerous disorders, tumors, fibrotic diseases, disorders of immune response imbalance, and the like. 本发明本发明涉及有效作为调节剂芳烃受体(AhR)的新化合物,包含该化合物作为活性成分的药物组合物,其用于调节AhR,或预防或治疗与AhR活性相关的疾病、紊乱或病症,因此,可用作药物用于预防或治疗与AhR活性相关的疾病、紊乱或病症,特别是癌症、癌性病症、肿瘤、纤维化疾病、免疫应答失调的病症等。