Congenital adrenal hyperplasia screening kit and application thereof

The invention discloses a congenital adrenal hyperplasia screening kit and application thereof, and relates to the technical field of blood detection. The congenital adrenal hyperplasia screening kit is characterized by comprising a calibration product, a quality control product, an isotope internal...

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Bibliographische Detailangaben
Hauptverfasser: BAO DONGQIN, CHEN JIANQI, LI HAIMING
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a congenital adrenal hyperplasia screening kit and application thereof, and relates to the technical field of blood detection. The congenital adrenal hyperplasia screening kit is characterized by comprising a calibration product, a quality control product, an isotope internal standard product, an extracting solution, an extracting solution and a mobile phase. The congenital adrenal hyperplasia screening kit provided by the invention adopts a liquid chromatography-tandem mass spectrometry technology, is high in detection flux, can simultaneously detect 17 alpha-OHP, testosterone, androstenedione, 11-deoxycortisol, 21-deoxycortisol and cortisol markers, and is high in detection sensitivity, strong in specificity and high in accuracy; a sample detected by the kit is a dried blood spot, the dried blood spot sample is convenient to collect and low in cost, and the blood sampling requirement is reduced; the kit disclosed by the invention is relatively simple in detection process, and detecti