Separation and identification of novel amino acid derivative in red ginseng and novel application of novel amino acid derivative

The invention relates to the field of natural medicinal chemistry, and particularly discloses separation and purification of novel amino acid derivative compounds in red ginseng and novel application of the novel amino acid derivative compounds. According to the present invention, an amino acid automatic analyzer, nuclear magnetic resonance and positive and negative ion mass spectrometry are adopted to identify the structure of the compound, such that the molecular formula and the structural formula of the compound are derived, and the compound is finally named as histidine-fluorescsyl-glucose (HFG); furthermore, an in-vitro cell viability screening result shows that the HFG has a relatively good protection effect on HUVECs cell injury induced by glucose and can be applied to preparation of medicines for protecting cardiovascular diseases. 本发明涉及天然药物化学领域，具体公开了一种红参(Red ginseng)中的新的氨基酸衍生物类化合物分离纯化及新用途。本发明采用氨基酸自动分析仪、核磁共振及正负离子质谱对此化合物进行结构鉴定，推导出其分子式及结构式，并最终命名为组氨酸双糖苷(Histidinyl-fructosyl-glucose，HFG)。进一步体外细胞活性筛选结果表明，H