Application of dimethyl sulfoxide to prevention of lung-type acute radiation sickness

The invention provides an application of dimethyl sulfoxide (DMSO) in preparation of a pharmaceutical composition for preventing lung tissue injury of radiation exposed people or rescuers who enter a nuclear pollution area to execute tasks after nuclear attack. On the other hand, the invention provides DMSO or a pharmaceutical composition containing the DMSO, and the DMSO or the pharmaceutical composition is used for preventing lung-type acute radiation sickness related to lung tissue damage of radiation exposed people after nuclear attack or rescuers entering a nuclear pollution area to execute tasks. The survival rate after X-ray chest irradiation can be remarkably improved by oral administration of DMSO before irradiation, and the pathological process of radiation pneumonitis is improved. 本发明提供了二甲基亚砜(DMSO)在制备用于预防核袭击后辐射暴露人群或进入核污染区执行任务的救援人员肺组织损伤的药物组合物中的用途。另一方面，本发明提供了DMSO或包含DMSO的药物组合物，其用于预防核袭击后辐射暴露人群或进入核污染区执行任务的救援人员肺组织损伤相关的肺型急性放射病。DMSO照前口服给药可显著提高X射线胸部照射后的存活率，改善放射性肺炎的病理进程。