Magnetic injectable granular hydrogel as well as preparation method and application thereof

The invention relates to the technical field of preparation of composite materials, in particular to magnetic injectable granular hydrogel as well as a preparation method and application thereof. The magnetic particle hydrogel composed of gelatin nanoparticles and magnetic montmorillonite particles...

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Bibliographische Detailangaben
Hauptverfasser: XU YUNJUN, LU YANG, CAO BAOQIANG, PENG ZONGSHUN, DONG LIANG, HU JINLONG, WU WENSHU, XING HANYE, CHEN SHENG, SONG YONGHONG, YAN XU, ZHA ZHENGBAO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of preparation of composite materials, in particular to magnetic injectable granular hydrogel as well as a preparation method and application thereof. The magnetic particle hydrogel composed of gelatin nanoparticles and magnetic montmorillonite particles is synthesized through electrostatic force self-assembly, the hydrogel has excellent viscoelasticity and self-healing performance and can intelligently respond to a magnetic field, magnetic heat accelerates the particle hydrogel to adapt to surgical wounds, magnetic heat promotes medicine to be evenly released, and the hydrogel has good hemostatic performance and can be used for preparing a medical dressing. The effect of the hemostatic sponge is superior to that of commercial hemostatic sponge, and the hemostatic sponge has a remarkable curative effect in anti-relapse treatment after mouse liver cancer resection. The components of the hydrogel are all medical auxiliary materials, the source is wide, the preparatio