Inhalable solution formulations containing tiotropium bromide and olodaterol

The present invention relates to a liquid, propellant-free pharmaceutical formulation and a method of administering the pharmaceutical formulation by aerosolizing the pharmaceutical formulation in an inhaler. The propellant-free pharmaceutical preparation comprises a solvent, tiotropium bromide or a pharmaceutically acceptable salt thereof, olodaterol or a pharmaceutically acceptable salt thereof, a pH adjusting agent and a pharmaceutically acceptable additive. 本发明涉及一种液体的、不含推进剂的药物制剂和一种通过在吸入器中雾化药物制剂来给药该药物制剂的方法。不含推进剂的药物制剂包括溶剂、噻托溴铵或其药学上可接受的盐、奥达特罗或其药学上可接受的盐、pH调节剂和药学上可接受的添加剂。