Application of cyclin-dependent kinase 9 inhibitor

The invention provides various applications of a compound as shown in a formula (I) or a pharmaceutically acceptable salt, a stereoisomer or a prodrug thereof as a cyclin dependent kinase 9 (CDK9) inhibitor in treatment of hematologic tumors, especially leukemia, myeloma and lymphoma, including rela...

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Bibliographische Detailangaben
Hauptverfasser: ZHAO CHUANWU, GAO NA, WANG JIA, HAO HONGRU, CHAI XIAOLING, FAN LIXUE, WEI BING
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides various applications of a compound as shown in a formula (I) or a pharmaceutically acceptable salt, a stereoisomer or a prodrug thereof as a cyclin dependent kinase 9 (CDK9) inhibitor in treatment of hematologic tumors, especially leukemia, myeloma and lymphoma, including related pharmaceutical uses, pharmaceutical compositions or treatment methods and the like. 本申请提供式(I)所示的化合物或其可药用盐、其立体异构体或前药作为周期蛋白依赖性激酶9(CDK9)抑制剂在治疗血液肿瘤,特别是白血病、骨髓瘤和淋巴瘤中的各种应用,包括相关的制药用途、药物组合物或治疗方法等。