Lithospermum naphthoquinone water-soluble solid dispersion, water-soluble preparation and preparation method

The invention relates to a lithospermum naphthoquinone water-soluble solid dispersion, a water-soluble preparation and a preparation method, and relates to the field of pharmaceutical preparations, the lithospermum naphthoquinone water-soluble solid dispersion is composed of a fat-soluble monomeric compound and poloxamer, the weight of the poloxamer is 1.0-60% of the weight of the fat-soluble monomeric compound, the weight of the water-soluble preparation is 10-30% of the weight of the fat-soluble monomeric compound, and the weight of the water-soluble preparation is 10-30% of the weight of the fat-soluble monomeric compound. The fat-soluble monomer compound is lithospermum naphthoquinone. The invention provides a lithospermum naphthoquinone preparation with higher bioavailability and stability, which is convenient for clinical aerosol inhalation, oral and nasal spray, injection or transdermal therapy. 本发明涉及一种紫草萘醌水溶性固体分散体、水溶制剂及制备方法，本发明涉及医药制剂领域，所述的紫草萘醌的水溶性固体分散体由脂溶性单体化合物和泊洛沙姆组成，所述泊洛沙姆的重量为脂溶性单体化合物的重量的1.0～60％，所述脂