Hydrogel for ultraviolet light-controlled slow release of hydrogen sulfide as well as preparation and application of hydrogel

The invention provides an ultraviolet light-controlled slow-release hydrogen sulfide hydrogel as well as preparation and application thereof. The hydrogel has a chemical structure as shown in a formula (I). The hydrogel disclosed by the invention is simple in preparation method and mild in reaction condition, and has good stability and biocompatibility; under the irradiation of ultraviolet light, the hydrogel can generate an active intermediate phenylthioaldehyde, and the phenylthioaldehyde reacts with amino acid or amine to release hydrogen sulfide; by controlling the illumination time, the release speed and concentration of hydrogen sulfide can be effectively regulated and controlled; after hydrogen sulfide is released, gel residues are kept in an original state and can be removed, so that the gel is non-toxic to biological cells. 本发明提供一种紫外光控缓释硫化氢的水凝胶及其制备与应用，所述水凝胶具有如式(I)所示的化学结构。本发明的水凝胶制备方法简单，反应条件温和，具有良好的稳定性和生物兼容性；在紫外光照射下，水凝胶可以生成活性中间体苯甲硫醛，苯甲硫醛与氨基酸或胺反应会释放硫化氢；通过控制光照时间，可以有效调控硫化氢的释放速度和浓度；释放硫化氢后，凝胶残余保持原态，可以移去，对生物