Methods and compositions for detecting viruses

Methods and compositions for detecting viruses

Described herein are lateral flow assays and compositions for performing such assays that detect the entire virus (e.g., HIV, HCV, HSV-2) or viral protein using a broad spectrum antiviral lectin griffithin (GRFT) conjugated to a polymer or gold nanoparticles (NP) and a suitable monoclonal antibody (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: STEINBACH-LANKINS JOHN M, HAMERSKY KLAUS, PALMER KEVIN, FOUCA JULIE
Format: Patent
Sprache:chi ; eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:Described herein are lateral flow assays and compositions for performing such assays that detect the entire virus (e.g., HIV, HCV, HSV-2) or viral protein using a broad spectrum antiviral lectin griffithin (GRFT) conjugated to a polymer or gold nanoparticles (NP) and a suitable monoclonal antibody (mAb) to confer virus selectivity. 本文描述了侧向流测定法和用于进行此类测定法的组合物，其使用广谱抗病毒凝集素griffisthin(GRFT)检测整个病毒(例如，HIV、HCV、HSV-2)或病毒蛋白，该griffisthin(GRFT)与聚合物或金纳米颗粒(NP)和适当的单克隆抗体(mAb)缀合以赋予病毒选择性。