Method for purifying tafluprost

[Problem] The purpose of the present invention is to provide a simple and efficient method for purifying tafluprost that can be scaled up in proportion. [Solution] The present invention relates to a method for purifying tafluprost, which comprises a step for purifying a crude product of tafluprost b...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MATSUMURA YASUSHI, MORI NOBUAKI, KONISHI KATSUHIKO
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:[Problem] The purpose of the present invention is to provide a simple and efficient method for purifying tafluprost that can be scaled up in proportion. [Solution] The present invention relates to a method for purifying tafluprost, which comprises a step for purifying a crude product of tafluprost by silica gel column chromatography and collecting a component containing tafluprost by HPLC analysis. In addition, the present invention also relates to a method for producing tafluprost, which comprises the aforementioned method for purifying tafluprost. [课题]本发明的目的在于提供一种简便且高效的、并且可以按比例放大的他氟前列素的纯化方法。[解决手段]本发明涉及一种他氟前列素的纯化方法,其包括利用硅胶柱色谱法对他氟前列素的粗产物进行纯化、并利用HPLC分析收集包含他氟前列素的组分的工序。另外,本发明还涉及包括前述他氟前列素的纯化方法的他氟前列素的制造方法。