Application of compound BML-275 in preparation of medicine for improving nasopharyngeal carcinoma prognosis

The invention belongs to the field of biological medicines, and discloses application of a compound BML-275 in preparation of a medicine for improving nasopharyngeal carcinoma prognosis. A nude mouse in-vivo experiment proves that a clinical high-correlation nude mouse nasopharyngeal carcinoma in-si...

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Hauptverfasser: GU MIAO, SHENG JUPING, YOU BO, XIA TIAN, YOU YIWEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the field of biological medicines, and discloses application of a compound BML-275 in preparation of a medicine for improving nasopharyngeal carcinoma prognosis. A nude mouse in-vivo experiment proves that a clinical high-correlation nude mouse nasopharyngeal carcinoma in-situ metastasis model and a nude mouse subcutaneous recurrence model which are successfully molded are taken as experimental subjects, and after intraperitoneal administration of BML-275 and cis-platinum is combined, the recurrence and metastasis rate is reduced, and the survival rate is improved. The invention has certain improvement on the treatment effect of nasopharyngeal carcinoma, and can inhibit recurrence and metastasis of nasopharyngeal carcinoma to a certain extent, thereby improving the survival rate of nasopharyngeal carcinoma patients, improving the prognosis of the nasopharyngeal carcinoma patients, and having important development and application prospects. 本发明属于生物医药领域,公开了一种化合物BML-275在制备改善鼻咽癌预后的药物中的应用。