Kit for constructing humanized flora mouse model

The invention discloses a kit which comprises a broad-spectrum antibiotic composition, human intestinal flora, dietary fiber pectin and an intragastric administration device. By adopting the kit, a humanized flora mouse model can be constructed, and a tumor model is constructed on the basis of the h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZHANG SHILONG, WANG XIN, LIU ZEJUAN, ZHANG ZHENGYAN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a kit which comprises a broad-spectrum antibiotic composition, human intestinal flora, dietary fiber pectin and an intragastric administration device. By adopting the kit, a humanized flora mouse model can be constructed, and a tumor model is constructed on the basis of the humanized flora mouse model and is used for screening or evaluating an immune checkpoint inhibitor. 本发明公开了一种的试剂盒,其包括广谱抗生素组合物、人类肠道菌群、膳食纤维果胶、灌胃器具。采用该试剂盒可构建人源化菌群小鼠模型,在此基础上构建肿瘤模型,用于免疫检查点抑制剂筛选或评价。