Compounds and compositions as PDGF receptor kinase inhibitors

The purpose of the present invention is to provide a compound having inhibitory activity against PDGF receptor kinase. For example, the present invention includes a compound represented by formula [1], a pharmaceutically acceptable salt of the compound, or a solvate of the compound. The compounds of the present invention have inhibitory activity against PDGF receptor kinase. Due to its activity against PDGF receptor kinase, the compound of the present invention is useful as a therapeutic agent for respiratory diseases, cancer, smooth muscle proliferative diseases, vascular proliferative diseases, autoimmune/inflammatory diseases, metabolic diseases, vascular obstructive diseases, and the like. 本发明的目的是提供具有针对PDGF受体激酶的抑制活性的化合物。例如，本发明包括由式[1]表示的化合物或所述化合物的药学上可接受的盐或所述化合物的溶剂化物。本发明的化合物具有针对PDGF受体激酶的抑制活性。由于其针对PDGF受体激酶的活性，本发明的化合物可用作用于呼吸疾病、癌症、平滑肌增殖性疾病、血管增殖性疾病、自身免疫/炎性疾病、代谢疾病、血管阻塞性疾病等的治疗剂。