Preparation method and application of nerve vascularization double-sided bionic periosteum

The invention relates to a preparation method and application of a nerve vascularization double-sided bionic periosteum. A template with a surface orientation structure is used as a collector to collect polyester nano spinning fibers, and the single-orientation nanofiber membrane and the double-orie...

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Hauptverfasser: DAI HONGLIAN, SUN LINGSHUN, LI QING, HOU WEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a preparation method and application of a nerve vascularization double-sided bionic periosteum. A template with a surface orientation structure is used as a collector to collect polyester nano spinning fibers, and the single-orientation nanofiber membrane and the double-orientation nanofiber membrane are structurally realized. The microenvironment for growth of natural periosteal cells is simulated from the structure and the function, and a new treatment strategy is provided for large-segment bone regeneration. 本发明涉及一种神经血管化双面仿生骨膜的制备方法及应用。将具有表面取向结构的模板作为收集器收集聚酯类纳米纺丝纤维,从结构上实现单、双取向纳米纤维膜。从结构和功能双重模拟天然骨膜细胞生长的微环境,为大段骨再生提供一种治疗的新策略。