Solution type anhydrous emulsifiable paste of active substances and preparation method of solution type anhydrous emulsifiable paste

The invention belongs to the technical field of external emulsifiable paste, and particularly relates to a solution type anhydrous emulsifiable paste of active substances and a preparation method thereof, the solution type anhydrous emulsifiable paste comprises the following components by mass: 8-30 parts of an emulsifier, 1-20 parts of a thickener, 1-40 parts of an oil phase matrix, 20-90 parts of an organic phase and 0-5 parts of an additive, and the emulsifier comprises a main emulsifier, a co-emulsifier and a surfactant. The cream provided by the invention is in an anhydrous solution state, can be used for active substances which are unstable to water or extremely low in solubility in water, and solves the difficulty of novel active substances in a preparation process. 本发明属于外用乳膏技术领域，具体涉及一种活性物质的溶液型无水乳膏及其制备方法，其质量配比为：乳化剂8-30份、增稠剂1-20份、油相基质1-40份、有机相20-90份、附加剂0-5份，且所述乳化剂由主乳化剂、助乳化剂和表面活性剂组成。本发明提供的乳膏呈无水溶液状态，可用于对水不稳定或在水中溶解度极低的活性物质，解决了新型活性物质在制剂过程中的难点。