Rabies vaccine protective agent, rabies vaccine and preparation method of rabies vaccine protective agent

The invention relates to a rabies vaccine protective agent, a rabies vaccine and a preparation method of the rabies vaccine protective agent. The rabies vaccine protective agent does not contain gelatin and dextran 40 and contains human serum albumin, trehalose, maltose and an antioxidant, the mass...

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Hauptverfasser: ZHANG TAO, YE HUIXIA, TANG PANFENG, ZHONG SHULING, TANG YONG, MAO ZI'AN, YU SHUMIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a rabies vaccine protective agent, a rabies vaccine and a preparation method of the rabies vaccine protective agent. The rabies vaccine protective agent does not contain gelatin and dextran 40 and contains human serum albumin, trehalose, maltose and an antioxidant, the mass ratio of the human serum albumin to the trehalose to the maltose to the antioxidant is (0.5-2): (0.2-1): (1-4): (0.05-0.4), and the antioxidant comprises vitamins. The rabies vaccine prepared from the rabies vaccine protective agent is good in titer stability and high in safety. 本发明涉及一种狂犬病疫苗保护剂、狂犬病疫苗及其制备方法。该狂犬病疫苗保护剂不含明胶和右旋糖酐40,包含有人血白蛋白、海藻糖、麦芽糖和抗氧化剂,其中,人血白蛋白、海藻糖、麦芽糖和抗氧化剂的质量之比为(0.5~2):(0.2~1):(1~4):(0.05~0.4),抗氧化剂包括维生素。采用该狂犬病疫苗保护剂制备的狂犬病疫苗效价稳定性好,安全性高。