Glipizide controlled release tablet and preparation method thereof

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to glipizide controlled release tablets and a preparation method thereof. The glipizide controlled release tablet comprises a drug-containing layer, a propelling layer, a controlled release film and a soluble film, the medicine-containing layer comprises glipizide, povidone, sodium chloride, polyethylene glycol, hydroxypropyl methylcellulose, red iron oxide and magnesium stearate; the propelling layer comprises povidone, sodium carboxymethyl cellulose, hydroxypropyl cellulose, sodium chloride, red iron oxide, magnesium stearate, hydroxypropyl methylcellulose, 95% ethanol and purified water; the controlled release film coating solution comprises cellulose acetate, polyethylene glycol, purified water and acetone; the soluble film coating liquid comprises a gastric-soluble film coating premix and purified water. The glipizide controlled release tablet conforms to a zero-order drug release model of the controlled