Bioreactor for cell treatment

The present invention provides a bioreactor (100) for cell treatment. The bioreactor (100) comprises a container (110) having a base section (102) comprising a transparent or translucent sensor window (103), a top section (101) arranged opposite the base section (102) and comprising a fluid inlet an...

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Bibliographische Detailangaben
Hauptverfasser: RICKETT TOBY, PALMER JASON, REMS, WILLIAM, WEHLEICH, FARON, ARMAN AMINI, GOWLER, VINCE
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention provides a bioreactor (100) for cell treatment. The bioreactor (100) comprises a container (110) having a base section (102) comprising a transparent or translucent sensor window (103), a top section (101) arranged opposite the base section (102) and comprising a fluid inlet and a fluid outlet, and a sidewall (105) extending between the base section (102) and the top section (101) and defining an interior volume of the container adapted to contain a cell suspension. At least one optical element (106, 107) is disposed on the sensor window (103) within the internal volume, the optical element (106, 107) being adapted to emit a fluorescence signal in response to the incident light, the fluorescence signal being associated with one or more parameters of the cell suspension. 本发明提供了一种用于细胞处理的生物反应器(100)。生物反应器(100)包括容器(110),该容器具有包括透明或半透明的传感器窗口(103)的基底部段(102)、与基底部段(102)相对布置并包括流体入口和流体出口的顶部部段(101)、以及在基底部段(102)和顶部部段(101)之间延伸并限定容器的适于容纳细胞悬浮液的内部容积的侧壁(105)。至少一个光学元件(106,107)在内部容积内设置在传感器窗口(103)上,光学元件(106,1