Load addiction producing strain

The present invention provides a microbial producing cell for synthesizing a product, which further comprises a load addiction gene pathway, the expression of which confers selective growth and/or survival advantages to those cells synthesizing the product; and meanwhile, the proliferation of low or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	RUGBERG PETER, SOMMER MIKA OSKAR ALFONS, OLSEN WALTER KARL PETER, JOHANSEN, ANDERS, L., T
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides a microbial producing cell for synthesizing a product, which further comprises a load addiction gene pathway, the expression of which confers selective growth and/or survival advantages to those cells synthesizing the product; and meanwhile, the proliferation of low or non-productive escape cells is limited. 本发明提供了一种用于合成产物的微生物生产细胞，其进一步包含负荷成瘾基因线路，其表达赋予合成所述产物的那些细胞选择性生长和/或存活优势；同时限制低或非生产性逃逸细胞的增殖。