Phenolic acid compound as well as preparation method, pharmaceutical composition and application thereof

The invention discloses a phenolic acid compound as well as a preparation method, a pharmaceutical composition and application thereof, the phenolic acid compound is extracted and separated from dogwood, and the invention discloses application of the phenolic acid compound in preparation of medicine...

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Hauptverfasser: ZHANG WEIKU, MA BINGZHI, PENG ZHONGCAN, ZHANG JIA, XU JIEKUN, HE JUN, LIAN WENWEN
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creator ZHANG WEIKU
MA BINGZHI
PENG ZHONGCAN
ZHANG JIA
XU JIEKUN
HE JUN
LIAN WENWEN
description The invention discloses a phenolic acid compound as well as a preparation method, a pharmaceutical composition and application thereof, the phenolic acid compound is extracted and separated from dogwood, and the invention discloses application of the phenolic acid compound in preparation of medicines for preventing and treating diabetes mellitus and complications thereof. Specifically, the invention discloses application of the compound in preparation of alpha-glucosidase inhibitor hypoglycemic drugs. The invention provides a phenolic acid compound, and further provides a method for extracting the phenolic acid compound from dogwood, which is simple to operate, good in reproducibility and high in extraction purity. Test results show that the phenolic acid compound provided by the invention has an obvious inhibition effect on alpha-glucosidase, and can be applied as a medicine for treating diabetic diseases. The method can also be used for preparing health-care food or functional food for reducing blood sugar.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
FOODS OR FOODSTUFFS
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
title Phenolic acid compound as well as preparation method, pharmaceutical composition and application thereof
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