Metabolite associated with diagnosis of Cushing syndrome

The invention discloses a metabolite related to diagnosis of Cushing's syndrome. Through metabonomics research, it is found for the first time that LysoPE 20: 5 can be used as a Cushing syndrome diagnosis related metabolite, the LysoPE 20: 5 shows significant difference in Cushing syndrome pati...

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Hauptverfasser:	LI HANYU, ZHOU RUILIN, WU QINGYANG, ZHAO XINYUE, HU XIAOMIN, LIU JIFANG, SUN YUESHEN, LU LIN, SU WAN, ZHENG WEIYANG, FAN YUE, YAO YONG, WANG ZEYUAN, DENG KAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA HUMAN NECESSITIES HYGIENE INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	The invention discloses a metabolite related to diagnosis of Cushing's syndrome. Through metabonomics research, it is found for the first time that LysoPE 20: 5 can be used as a Cushing syndrome diagnosis related metabolite, the LysoPE 20: 5 shows significant difference in Cushing syndrome patients and healthy groups, and by detecting the level of LysoPE 20: 5, whether a subject suffers from the Cushing syndrome or has the risk of suffering from the Cushing syndrome can be judged. 本发明公开了与库欣综合征诊断相关的代谢物。本发明通过代谢组学研究，首次发现了LysoPE 20:5可作为库欣综合征诊断相关的代谢物，LysoPE 20:5在库欣综合征患者和健康群组中呈现显著性差异，通过检测LysoPE 20:5的水平，可以判断受试者是否患有库欣综合征或者存在患有库欣综合征的风险。