Agents for inducing immunity specific to Sars-cov-2

The present invention relates to immunology, and describes an agent in liquid form for inducing specific immunity against SARS-CoV-2, containing a single active ingredient, comprising an expression vector of human adenovirus serotype 26 in which the E1 and E3 regions are deleted, the ORF6-Ad26 regio...

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Bibliographische Detailangaben
Hauptverfasser:	LUBINAT NELSON L, ESMAGAMBETOV IGOR BORISOVICH, SEBLYAKOV DMITRY VLADIMIROVICH, ZUBKOVA OLGA VLADIMIROVNA, NIKITENKO NIKOLAY A, ELOKSOVA, ANNA, S, TUKHVATULLIN, ALEKSANDR IVANOVICH, SHCHERBININ DMITRY NIKOLAEVICH, SEMIHIN ALEKSANDR SERGEEVICH, TUHVATURINA NATALIA M, NARODITSKY BORIS SERGEEVICH, LOGUNOV, DIMITRI, Y, GINZBURG, ALAN, L, ZARURAYEVA, ANNA, S, POPOVA OLGA, TOKARSKAYA, ELENA, A, OZAROVSKAIA TATYANA ALEXANDROVNA, GRUSOVA DARYA MIKHAILOVNA, DORZHIKOVA IRINA VLADIMIROVNA, BERTIKOV ALEXEI GRIGORIEVICH, BORISEVICH SERGEY VLADIMIROVICH, IZAIWA FERENC M
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to immunology, and describes an agent in liquid form for inducing specific immunity against SARS-CoV-2, containing a single active ingredient, comprising an expression vector of human adenovirus serotype 26 in which the E1 and E3 regions are deleted, the ORF6-Ad26 region is replaced by ORF6-Ad5, and having an integrated expression cassette selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3. In another variant, the reagent contains a single active ingredient comprising an expression vector of human adenovirus serotype 5 wherein E1 and E3 regions are deleted, and has an integrated expression cassette selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3. In another variant, the agent contains a single active ingredient comprising an expression vector of simian adenovirus serotype 25 wherein E1 and E3 regions are deleted, and has an integrated expression cassette selected from the group consisting of SEQ ID NO: 4, SEQ ID NO: 2, SE