Perfluoroalkyl ketone inhibitors of elastase and preparing method thereof

本发明涉及作为弹性蛋白酶特别是人中性白细胞弹性蛋白酶抑制剂的化合物，本发明还涉及制备上述化合物的新方法，作为人中性白细胞弹性蛋白酶抑制剂，本发明化合物可用于治疗患有与中性白细胞有关的炎症的患者。 PCT No. PCT/US95/05363 Sec. 371 Date Nov. 22, 1996 Sec. 102(e) Date Nov. 22, 1996 PCT Filed May 1, 1995 PCT Pub. No. WO95/33762 PCT Pub. Date Dec. 14, 1995This invention relates to compounds which are i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	JR. W. A. METZ, T. T. CURRAN, J. P. BURKHART
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	本发明涉及作为弹性蛋白酶特别是人中性白细胞弹性蛋白酶抑制剂的化合物，本发明还涉及制备上述化合物的新方法，作为人中性白细胞弹性蛋白酶抑制剂，本发明化合物可用于治疗患有与中性白细胞有关的炎症的患者。 PCT No. PCT/US95/05363 Sec. 371 Date Nov. 22, 1996 Sec. 102(e) Date Nov. 22, 1996 PCT Filed May 1, 1995 PCT Pub. No. WO95/33762 PCT Pub. Date Dec. 14, 1995This invention relates to compounds which are inhibitors of elastase, particularly human neutrophil elastase, and to novel processes for making the same. As inhibitors of human neutrophil elastase, the compounds are useful in the treatment of a patient afflicted with a neutrophil associated inflammatory disease.