Multi-gene detection kit for venous thromboembolism and application of multi-gene detection kit

The invention provides a multi-gene detection kit for venous thromboembolism and application of the multi-gene detection kit. The kit comprises the following 65 genes as target genes: F2, F5, F8, SERPINC1, PROS1, PROC, PLCG2, VWF, GP6, GRK5, SH2B3, A4GALT, NLRP2, MYRF, SCARA5, TSPAN15, COL6A2, CDH23...

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Hauptverfasser: LI HAOBO, YANG PEIRAN, JIANG TAIJIAO, ZHAI ZHENGUO, WAN ZHAOMAN, SU MINGMING, ZHANG ZHU, ZHANG XINLEI, ZHANG YU, XIE WANMU, HUANG ZECHI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a multi-gene detection kit for venous thromboembolism and application of the multi-gene detection kit. The kit comprises the following 65 genes as target genes: F2, F5, F8, SERPINC1, PROS1, PROC, PLCG2, VWF, GP6, GRK5, SH2B3, A4GALT, NLRP2, MYRF, SCARA5, TSPAN15, COL6A2, CDH23, CFTR, FGA, LYST, PIEZO1, JAK2, TET2, ACE, CASR and the like. The kit provided by the invention solves the technical problems that an existing detection kit in the prior art is poor in accuracy and rare mutations associated with certain pathogenicity are difficult to find. Powerful related gene detection results can be provided for clinical venous thromboembolism diagnosis and prevention of hospitalized patients, and prevention and treatment schemes are determined by combining clinical assistance. 本发明提供一种静脉血栓栓塞症多基因检测试剂盒及其应用,该试剂盒中包含以下65个基因作为靶向基因:F2、F5、F8、SERPINC1、PROS1、PROC、PLCG2、VWF、GP6、GRK5、SH2B3、A4GALT、NLRP2、MYRF、SCARA5、TSPAN15、COL6A2、CDH23、CFTR、FGA、LYST、PIEZO1、JAK2、TET2、ACE、CASR等。本发明试剂盒解决了现有技术中已有的检测试剂盒精确性欠缺、存在对