Bladder perfusion medicine compound preparation as well as preparation method and application thereof

The invention discloses a bladder perfusion medicine compound preparation which comprises an anthracycline chemotherapeutic drug capable of causing immunogenic death of tumor cells, an immunomodulator and a pH regulator. The compound preparation has good chemical stability, and solves the problem of...

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Bibliographische Detailangaben
Hauptverfasser: TAO HUIQUAN, DENG ZHONGQING, ZHOU XUANFANG, LIU ZHUANG, WU YUCHEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a bladder perfusion medicine compound preparation which comprises an anthracycline chemotherapeutic drug capable of causing immunogenic death of tumor cells, an immunomodulator and a pH regulator. The compound preparation has good chemical stability, and solves the problem of impurity growth caused by the influence of immunologic adjuvants on anthracycline chemical drugs. 本发明公开了一种膀胱灌注药物复方制剂,包括能引起肿瘤细胞免疫原性死亡的蒽环类化疗药,免疫调节剂及pH调节剂。这种复方制剂具有良好的化学稳定性,解决了蒽环类化药受到免疫佐剂影响导致杂质增长的问题。