Pharmaceutical composition containing nemategravir and preparation method thereof

The invention provides a pharmaceutical composition containing nemategravir. The pharmaceutical composition can be prepared into nemategravir tablets. The pharmaceutical composition provided by the invention comprises drug-containing particles and extra-particle components, the medicine-containing p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZONG ZAIWEI, FAN HENGFENG, CHEN QINGCAI, QIU HAIZHEN, WU PENGPENG, TIAN SHUAIHUA
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides a pharmaceutical composition containing nemategravir. The pharmaceutical composition can be prepared into nemategravir tablets. The pharmaceutical composition provided by the invention comprises drug-containing particles and extra-particle components, the medicine-containing particles comprise one or more of nemategravir, a filling agent, a disintegrating agent, a flow aid and an in-particle lubricant; and the extra-particle component comprises an extra-particle lubricant. The invention also provides a preparation method of the pharmaceutical composition. The composition has the characteristics of simple preparation method, good stability and the like. 本发明提供了一种含有奈玛特韦的药物组合物,所述药物组合物可以制成奈玛特韦片。本发明所述药物组合物包括含药颗粒、颗粒外组分;所述含药颗粒包括奈玛特韦、填充剂、崩解剂、助流剂和颗粒内润滑剂中的一种或多种;所述颗粒外组分包括颗粒外润滑剂。本发明还提供了该药物组合物的制备方法。所述组合物具有制备方法简便,稳定性良好等特点。