Antigen binding polypeptide binding CD47 and application

Provided are an antigen-binding polypeptide or an antigen-binding portion thereof that binds CD47, and a nucleic acid, a carrier, a cell, and a pharmaceutical composition that encode the polypeptide, the polypeptide being capable of reducing tumors or inhibiting tumor cell growth, treating cancers,...

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Bibliographische Detailangaben
Hauptverfasser:	YANG LING, ZOU XIAOFANG, WANG LIANGLIANG, ZHANG XIAOYUN, KATSURAAKI, ZHU HONG, SHEN HENGQIAO, XU HONGJIANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided are an antigen-binding polypeptide or an antigen-binding portion thereof that binds CD47, and a nucleic acid, a carrier, a cell, and a pharmaceutical composition that encode the polypeptide, the polypeptide being capable of reducing tumors or inhibiting tumor cell growth, treating cancers, promoting macrophage phagocytosis, and the like. 提供一种结合CD47的抗原结合多肽或其抗原结合部分，以及编码多肽的核酸、载体、细胞、药物组合物，该多肽可减少肿瘤或抑制肿瘤细胞生长、治疗癌症、促进巨噬细胞吞噬作用等。