Pyxinol amide derivative as well as preparation method and application thereof in field of medicines

The invention discloses a Pyxinol amide derivative and a preparation method thereof, the structural formula of the Pyxinol amide derivative is shown as a formula I, or a pharmaceutically acceptable salt of the compound shown as the formula I, and discloses the Pyxinol amide derivative and the pharmaceutically acceptable salt thereof, and application of the Pyxinol amide derivative and the pharmaceutically acceptable salt thereof in preparation of tumor drug resistance reversal agents/tumor drug sensitizers, tumor drug delivery systems, tumor drug delivery systems and the like. Or application in preparation of a tumor drug resistance reversal agent/tumor drug sensitizer containing a pharmaceutically acceptable carrier. The Pyxinol amide derivative disclosed by the invention has remarkable anti-tumor drug resistance reversion capability and activity for inhibiting the function of P-glycoprotein. Meanwhile, the compound shows a longer half-life period in in-vitro metabolism stability evaluation, and the activity