Preparation method of 2-alkyl indan-1-one compound
The invention discloses a preparation method of a 2-alkyl indan-1-one compound, which comprises the following steps: in the presence of a guiding group and a rhodium catalyst, carrying out intramolecular olefin one-carbon insertion non-tension ketone carbon-carbon bond reaction on a raw material com...
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creator | XIA YING WU XIULI YE QIAN HUANG JIANGKUN |
description | The invention discloses a preparation method of a 2-alkyl indan-1-one compound, which comprises the following steps: in the presence of a guiding group and a rhodium catalyst, carrying out intramolecular olefin one-carbon insertion non-tension ketone carbon-carbon bond reaction on a raw material compound I-0, and treating after the reaction to obtain the 2-alkyl indan-1-one compound. The preparation method of the 2-alkyl indan-1-one compound, disclosed by the invention, is high in selectivity, and is beneficial to improving the conversion rate of reaction and improving the yield of a target product; the purification operation of the 2-alkyl substituted indan-1-one compound is facilitated, and the purity of a target product is improved; the synthesis route is simple and easy to synthesize; the method is simple and easy to operate, mild in condition, free of potential safety hazards and environmental pollution and beneficial to industrial wide popularization and production application.
本发明公开了一种2-烷基茚满-1-酮类化合物的制备 |
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本发明公开了一种2-烷基茚满-1-酮类化合物的制备</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAKKEotSCxKLMnMz1PITS3JyE9RyE9TMNJNzMmuzFHIzEtJzNM11M3PS1VIzs8tyC_NS-FhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOfoaGpoYWhgaGJo7GxKgBAHdyKzg</recordid><startdate>20221014</startdate><enddate>20221014</enddate><creator>XIA YING</creator><creator>WU XIULI</creator><creator>YE QIAN</creator><creator>HUANG JIANGKUN</creator><scope>EVB</scope></search><sort><creationdate>20221014</creationdate><title>Preparation method of 2-alkyl indan-1-one compound</title><author>XIA YING ; WU XIULI ; YE QIAN ; HUANG JIANGKUN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN115181014A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>XIA YING</creatorcontrib><creatorcontrib>WU XIULI</creatorcontrib><creatorcontrib>YE QIAN</creatorcontrib><creatorcontrib>HUANG JIANGKUN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>XIA YING</au><au>WU XIULI</au><au>YE QIAN</au><au>HUANG JIANGKUN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation method of 2-alkyl indan-1-one compound</title><date>2022-10-14</date><risdate>2022</risdate><abstract>The invention discloses a preparation method of a 2-alkyl indan-1-one compound, which comprises the following steps: in the presence of a guiding group and a rhodium catalyst, carrying out intramolecular olefin one-carbon insertion non-tension ketone carbon-carbon bond reaction on a raw material compound I-0, and treating after the reaction to obtain the 2-alkyl indan-1-one compound. The preparation method of the 2-alkyl indan-1-one compound, disclosed by the invention, is high in selectivity, and is beneficial to improving the conversion rate of reaction and improving the yield of a target product; the purification operation of the 2-alkyl substituted indan-1-one compound is facilitated, and the purity of a target product is improved; the synthesis route is simple and easy to synthesize; the method is simple and easy to operate, mild in condition, free of potential safety hazards and environmental pollution and beneficial to industrial wide popularization and production application.
本发明公开了一种2-烷基茚满-1-酮类化合物的制备</abstract><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY METALLURGY ORGANIC CHEMISTRY |
title | Preparation method of 2-alkyl indan-1-one compound |
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