Method, biomarker, kit and device for assisting diagnosis of alzheimer-type dementia or mild cognitive impairment

The present invention addresses the problem of providing a method, a biomarker, a kit, and a device for easily assisting the diagnosis of Alzheimer-type dementia or mild cognitive impairment. The present invention relates to a method for assisting the diagnosis of Alzheimer's dementia, the meth...

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Hauptverfasser: UKEGAWA RYO, SASAMOTO HIRODAI, HIRAYASU KAZUNARI, NISHIBU TAKAHIRO, IMAWAKA NAOKO, ONODERA, SATOSHI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention addresses the problem of providing a method, a biomarker, a kit, and a device for easily assisting the diagnosis of Alzheimer-type dementia or mild cognitive impairment. The present invention relates to a method for assisting the diagnosis of Alzheimer's dementia, the method comprising a step for determining that a subject is Alzheimer's dementia using the amount of extracellular vesicles having phosphatidylserine and four-time transmembrane protein as an index. A method for assisting Alzheimer's dementia or mild cognitive impairment, comprising a step for determining that a subject is Alzheimer's dementia or mild cognitive impairment, using, as an index, the ratio of the amount of extracellular vesicles having phosphatidylserine and transmembrane protein to the amount of extracellular vesicles having transmembrane protein, and a method for assisting Alzheimer's dementia or mild cognitive impairment Methods, biomarkers, kits and devices for diagnosis. 本发明的课题在于提供一种简单地辅助阿尔茨海默型痴呆症或轻度认知障碍的诊断