Lincomycin pharmaceutical co-crystal and preparation method thereof

The invention provides a lincomycin pharmaceutical co-crystal and a preparation method thereof. The lincomycin pharmaceutical co-crystal is prepared from lincomycin and sodium cyclamate, a powder X-ray diffraction pattern of the lincomycin-sodium cyclamate eutectic crystal has characteristic peaks at diffraction angles 2theta of 6.9 +/-0.2 degrees, 8.8 +/-0.2 degrees, 10.0 +/-0.2 degrees, 11.1 +/-0.2 degrees, 12.1 +/-0.2 degrees, 13.8 +/-0.2 degrees, 14.9 +/-0.2 degrees, 16.1 +/-0.2 degrees, 17.2 +/-0.2 degrees, 18.0 +/-0.2 degrees, 19.4 +/-0.2 degrees, 20.5 +/-0.2 degrees, 21.2 +/-0.2 degrees, 22.5 +/-0.2 degrees, 23.5 +/-0.2 degrees, 24.6 +/-0.2 degrees, 25.3 +/-0.2 degrees, 27.3 +/-0.2 degrees, 27.9 +/-0.2 degrees, 29.2 +/-0.2 degrees, 29.8 Compared with existing lincomycin, the lincomycin-sodium cyclamate eutectic crystal has more stable physical properties, the water solubility of the lincomycin-sodium cyclamate eutectic crystal is improved under the same condition, and the prepared lincomycin-sodium cyc