High-activity glycosyl cryptolepis sinensis zinc (II) complex and application

High-activity glycosyl cryptolepis sinensis zinc (II) complex and application

The invention relates to a high-activity glycosyl cryptolepine zinc (II) complex. The chemical structural formula of the high-activity glycosyl cryptolepine zinc (II) complex is shown in the specification. The invention further discloses application of the high-activity glycosyl cryptolepine zinc (I...

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Bibliographische Detailangaben
Hauptverfasser: ZHOU ZHEN, QIN QIPIN, LONG HONGMIN, TAN MINGXIONG, TAN FANGXIANG, ZOU SIQI, ZHU LIGANG, FENG QINGLI, DU LINGQI, CHEN HAISHENG
Format: Patent
Sprache:chi ; eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to a high-activity glycosyl cryptolepine zinc (II) complex. The chemical structural formula of the high-activity glycosyl cryptolepine zinc (II) complex is shown in the specification. The invention further discloses application of the high-activity glycosyl cryptolepine zinc (II) complex. The high-activity glycosyl cryptolepine zinc (II) complex shows excellent in-vivo and in-vitro anti-tumor activity and targeting property, has potential medicinal value, and is expected to be used for preparing various anti-tumor drugs. 本发明涉及一种高活性糖基白叶藤碱锌(II)配合物，其化学结构式如下式所示：本发明还公开了所述高活性糖基白叶藤碱锌(II)配合物的应用。所述高活性糖基白叶藤碱锌(II)配合物表现出优越的体内外抗肿瘤活性和靶向性，具有潜在的药用价值，有望用于各种抗肿瘤药物的制备。