Method and reaction system for preparing 2-chloro-5-nitrobenzonitrile

The invention relates to the technical field of chemical engineering, in particular to a method for preparing 2-chloro-5-nitrobenzonitrile and a reaction system.The method comprises the following steps that concentrated sulfuric acid, fuming nitric acid and molten-state o-chlorobenzonitrile are conveyed into a microchannel reactor to be mixed and subjected to a nitration reaction, and reaction liquid is obtained; and after the reaction is finished, carrying out purification treatment on the reaction liquid. The method can obviously shorten the nitration reaction time of the o-chlorobenzonitrile, improve the reaction efficiency of the nitration reaction, improve the yield of a target product in unit time and improve the reaction safety, and also has the effects of environmental protection and energy conservation. 本发明涉及化工技术领域，具体涉及一种制备2-氯-5-硝基苯甲腈的方法及反应系统，该方法包括如下操作：将浓硫酸、发烟硝酸以及熔融态邻氯苯腈分别输送至微通道反应器中混合并进行硝化反应，得反应液；反应结束后，对所述反应液进行纯化处理。该方法能够显著缩短邻氯苯腈硝化反应的时间，提升硝化反应的反应效率，提升单位时间内目标产物的产量，提升反应安全性，同时还具有环保、节能的效果。