Nucleic acid aptamer capable of being specifically combined with FPV-VP2 protein

Nucleic acid aptamer capable of being specifically combined with FPV-VP2 protein

The invention provides a nucleic acid aptamer capable of being specifically combined with an FPV-VP2 protein. The sequence of the nucleic acid aptamer is 5 '-ATCGTCTGCTCCGTCCAATA-(N) 45-TTTGGTGTGAGGTCGTGC-3', and the nucleic acid aptamer can be specifically combined with the FPV-VP2 protei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZHAO ZHONGLIANG, WANG YANLING, LI JUNHUA, LIU ZUBIN, WANG YU, ZHANG ZIJUN, LOU QUN, SONG SHUFENG, YU JINGJING, HAO QINFANG, LI KAI, DONG ZHAOYANG
Format: Patent
Sprache:chi ; eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The invention provides a nucleic acid aptamer capable of being specifically combined with an FPV-VP2 protein. The sequence of the nucleic acid aptamer is 5 '-ATCGTCTGCTCCGTCCAATA-(N) 45-TTTGGTGTGAGGTCGTGC-3', and the nucleic acid aptamer can be specifically combined with the FPV-VP2 protein. Wherein the sequence of the (N) 45 is any one of SEQ ID NO: 1-4. The nucleic acid aptamer screened by the invention has excellent specificity and affinity to the FPV-VP2 protein, and provides an important technical support for further research of an FPV detection technology. 本发明提供一种可特异性结合FPV-VP2蛋白的核酸适配体，其序列为5′-ATCGTCTGCTCCGTCCAATA-(N)45-TTTGGTGTGAGGTCGTGC-3′；其中(N)45的序列为SEQ ID NO:1-4中的任一个。本发明筛选的核酸适配体对FPV-VP2蛋白具有极好的特异性和亲和力，为FPV检测技术的进一步研究提供了重要技术支撑。