Liquid chromatography-mass spectrometry detection method capable of directly analyzing salt-containing sample based on heat-assisted neutral double-spray rapid evaporation

The invention discloses a liquid chromatography-mass spectrometry detection method capable of directly analyzing a salt-containing sample based on heat-assisted neutral double-spray rapid evaporation, which comprises the following steps: double-spray generation: feeding a salt-containing sample solu...

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Hauptverfasser: GAO ZHAN, CHEN WEIWEI, XIONG MINGTENG, LIANG XIAO, PAN YUANJIANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a liquid chromatography-mass spectrometry detection method capable of directly analyzing a salt-containing sample based on heat-assisted neutral double-spray rapid evaporation, which comprises the following steps: double-spray generation: feeding a salt-containing sample solution into a sample spray generation module, and atomizing to form spray; an organic solvent is pumped to the organic solvent spray generation module and is atomized to form spray; double-spray focusing: focusing the sample spray and the organic solvent spray on an electric heating sheet; and desalting and ionizing: spraying the two strands of spray onto an electric heating sheet, crystallizing salt in the sample solution spray on the surface of the high-temperature electric heating sheet, depositing a to-be-detected object on the surface of the salt crystal, enabling the to-be-detected object to enter a gas phase under the combined action of thermal desorption of the electric heating sheet and spray elution of the