Anticoagulant polypeptide KT12 and application thereof

The invention provides an anticoagulant polypeptide KT12 and application thereof, and belongs to the technical field of biomedicine. The polypeptide KT12 provided by the invention has an obvious prolonging effect on plasma recalcification time, and an animal model also proves that the polypeptide KT12 has very strong anticoagulant activity, so that the application of the polypeptide KT12 in preparation of anticoagulant and/or antithrombotic drugs provides a new means for clinical treatment of cardiovascular and cerebrovascular diseases. 本发明提供了一种抗凝血多肽KT12及其应用，属于生物医学技术领域。本发明提供的多肽KT12对血浆复钙时间有明显的延长作用，通过动物模型也证实其具有很强的抗凝活性，因此多肽KT12在制备抗凝血和/或抗血栓的药物中的应用，为临床心脑血管疾病的治疗提供新手段。