Sanggenone C PLGA microsphere and preparation method of sanggenone C PLGA powder inhalation

The invention discloses sanggenone C PLGA microspheres and a preparation method of a sanggenone C PLGA powder inhalation, and relates to the technical field of medicines.The preparation method of the sanggenone C PLGA microspheres is characterized in that the preparation method of the sanggenone C P...

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Bibliographische Detailangaben
Hauptverfasser: HAN XUEWEI, ZHANG YUANDONG, LI LEICHANG, CHEN LI, WU YUMEI, XIONG YONG'AI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses sanggenone C PLGA microspheres and a preparation method of a sanggenone C PLGA powder inhalation, and relates to the technical field of medicines.The preparation method of the sanggenone C PLGA microspheres is characterized in that the preparation method of the sanggenone C PLGA microspheres specifically comprises the following steps that S1, sanggenone C and PLGA are weighed; s2, adding ethyl acetate and dichloromethane into the weighed sanggenone C and PLGA, and carrying out vortex until complete dissolution to form an organic phase; s3, pouring the organic phase into a PVA solution, and shearing to form O/W type primary emulsion; and S4, dropwise adding the primary emulsion obtained in S3 into a PVA solution, and stirring at room temperature to completely volatilize the organic solvent to obtain the sanggenone C PLGA microspheres. The method for preparing the sanggenone C PLGA microspheres and the method for preparing the sanggenone C PLGA microsphere powder inhalation can provide a