Pre-filled heparin sodium tube sealing injection and preparation method thereof

The invention belongs to the technical field of medicines, and particularly discloses a pre-filled heparin sodium tube sealing injection and a preparation method thereof. The pre-filled heparin sodium tube sealing injection is composed of heparin sodium, sodium hydroxide and normal saline according to the prescription dosage, the concentration of the heparin sodium is 10-100 unit/mL, the prepared heparin sodium salt aqueous solution is filled into a pre-filled syringe of random copolymer polypropylene which is good in transparency, high in glossiness and resistant to precipitation, and the finished product is prepared after high-pressure steam sterilization. By controlling the pH and high-pressure sterilization conditions of the prepared heparin sodium salt aqueous solution, the impurity content in the heparin sodium tube-sealing injection is finally remarkably reduced, the stability of the heparin sodium tube-sealing injection is improved, and the medication safety of the heparin sodium tube-sealing injectio