Sesame protein-sourced polypeptide with blood pressure and blood sugar lowering activity

The invention belongs to the technical field of deep processing of agricultural products, and particularly relates to a sesame active polypeptide which is composed of nine amino acids, and the sequence of the polypeptide is Ala-Phe-Pro-Ala-Gly-Ala-Ala-His-Trp (AFPAGAAHW). The sesame polypeptide disc...

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Bibliographische Detailangaben
Hauptverfasser:	LU FENGYIN, ZHANG LIXIA, LU XIN, SUN QIANG, ZHANG XIAOFENG, HUANG JINMIAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention belongs to the technical field of deep processing of agricultural products, and particularly relates to a sesame active polypeptide which is composed of nine amino acids, and the sequence of the polypeptide is Ala-Phe-Pro-Ala-Gly-Ala-Ala-His-Trp (AFPAGAAHW). The sesame polypeptide disclosed by the invention can be obtained by separating and purifying enzymolysis sesame protein, and can also be artificially synthesized by adopting a chemical solid-phase synthesis method. The determination of ACE inhibitory activity and DPP-IV inhibitory activity shows that the polypeptide shows the activity of reducing blood pressure and blood sugar, can be used as a functional component in the fields of preparation of medicines, health care products, food, daily chemical products and the like, and has a wide market prospect. 本发明属于农产品深加工技术领域，具体涉及一种芝麻活性多肽，该多肽由9个氨基酸组成，其序列为：Ala-Phe-Pro-Ala-Gly-Ala-Ala-His-Trp(AFPAGAAHW)。本发明芝麻多肽既能通过酶解芝麻蛋白分离纯化后获得，也可以采用化学固相合成方法人工合成。通过测定ACE抑制活力与DPP-IV抑制活力发现：该多肽显示降血压与降血糖活性，可以作为功能成分用于制备药物