Peptidomimetic compound and application thereof in preparation of 2019-nCoV main protease inhibitor

The invention belongs to the technical field of drug research and development, relates to a novel peptidomimetic compound, a pharmaceutically acceptable salt, a stereoisomer or an isotope label thereof, and further discloses application of the peptidomimetic compound in preparation of a 2019-nCoV main protease inhibitor. According to the peptidomimetic compound and the derivative, the pharmaceutically acceptable salt, the stereoisomer, the tautomer or the isotope label thereof, on the basis of the structure of the known 2019-nCoV main protease inhibitor PF-07321332, halogen or aliphatic substituent groups are introduced to obtain a compound with a new structure, and compared with the applied inhibitor PF-07321332, the novel structure of the peptidomimetic compound is improved, and the application range of the novel structure of the peptidomimetic compound is widened. According to the present invention, the inhibition activity, the pharmacokinetic property and the like of the compound on the main protease of t