Primary cervical cancer cell line with radiotherapy sensitivity and radiotherapy tolerance characteristics and construction method and application thereof

The invention provides a primary cervical cancer cell line with radiotherapy sensitivity and radiotherapy tolerance characteristics and a construction method and application thereof, the name of the radiotherapy tolerance cell line is UCR7, the name of the radiotherapy sensitive cell line is UCS19,...

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Bibliographische Detailangaben
Hauptverfasser:	YANG QIN, XING BIYUAN, PU CONGLI, CHANG YU, FAN JIQUAN, WANG HONGBO, LI GUILING, ZHAO YINGCHAO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS PROCESSES OF PREPARING SUCH COMPOSITIONS PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPIRITS TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides a primary cervical cancer cell line with radiotherapy sensitivity and radiotherapy tolerance characteristics and a construction method and application thereof, the name of the radiotherapy tolerance cell line is UCR7, the name of the radiotherapy sensitive cell line is UCS19, the primary cervical cancer cell line is preserved in China Center for Type Culture Collection, the address is Wuhan University, Wuhan, China, the preservation number of the UCR7 is CCTCC NO: C202286, and the preservation number of the UCS19 is CCTCC NO: C2022127. The radiation-tolerant cervical cancer conditional reprogramming cell line disclosed by the invention not only can retain the biological characteristics of tumor radiation tolerance of a patient, but also can be applied to construction of a second-generation biological specimen library and precision medicine as a cell model for basic research on related mechanisms of the radiation-tolerant cervical cancer, provides a more individualized treatment scheme f