Minoxidil supramolecular hydrogel for treating alopecia and preparation method of minoxidil supramolecular hydrogel

The invention discloses minoxidil-salicylic acid supramolecular hydrogel and a preparation method of the minoxidil-salicylic acid supramolecular hydrogel. The minoxidil-salicylic acid supramolecular hydrogel is highly ordered in structure and has a three-dimensional network pore structure, the pore size ranges from 200 nm to 500 nm, and the porosity is 48.3 +/-3.7%; hydroxyl and carboxyl of minoxidil-salicylic acid in the supramolecular hydrogel are combined with carboxyl of the carbomer matrix through hydrogen bond interaction; the dynamic viscosity of the supramolecular hydrogel at the temperature of 20 +/-0.1 DEG C is 4000.6 +/-40.0 mPa.s; compared with the existing commercially available drugs, the supramolecular hydrogel has better capability of penetrating through a semipermeable membrane and better thermal stability; animal experiment results show that the activity of the supramolecular hydrogel for promoting hair growth and hair follicle regeneration is superior to that of commercially available minox