一种哈维氏弧菌感染的生物标志物

本发明属于生物技术领域，公开了一种哈维氏弧菌感染的生物标志物，具体公开了一种哈维氏弧菌感染的生物标志物，所述生物标志物包括氨基肽酶、钙转运ATP酶、组蛋白H2B和组蛋白H2A中的至少一种。本发明在感染哈维氏弧菌的病鱼的细菌感染特征中，对海洋硬骨鱼半滑舌鳎粘液中的DEPs进行了鉴定和开发，并进过qRT-PCR验证，结果表明氨肽酶和钙转运ATP酶显著上调，组蛋白H2B和组蛋白H2A显著下调，可上述4种蛋白作为生物标志物来鉴定硬骨鱼是否感染哈维氏弧菌。 The invention belongs to the technical field of biology, discloses a biomarker for vibrio harveyi infection, and particularly discloses a biomarker for vibrio harveyi infection, and the biomarker comprises at least one of aminopeptidase, calcium transport ATP enzyme, histone H2B and histone H2A. In bacterial infection characteristics of diseased fish infected with vibrio harveyi, DEPs in mucus of marine sclerobone cynoglossus semilaevis are identified and developed, qRT-PCR verification is carried out, and results show that aminopeptidase and calcium transport ATP enzyme are significantly up-regulated, histone H2B and histone H2A are significantly down-regulated, and the result shows that DEPs in mucus of marine sclerobone cynoglossus semilaevis are significantly up-regulated. The four p