Synthesis method of water-soluble benzoxazine

The invention relates to a synthesis method of water-soluble benzoxazine, which comprises the following steps: mixing 100 parts by mass of phenolic compound, 30-2000 parts by mass of amine compound, 10-150 parts by mass of formaldehyde, 0-5 parts by mass of alkali and 100 parts by mass of organic solvent, heating to 85-100 DEG C, and reacting at constant temperature for 2-10 hours; and after the constant-temperature reaction is completed, carrying out vacuum distillation until no liquid is distilled out, so as to obtain the water-soluble benzoxazine. The method solves the technical problem that benzoxazine is difficult to dissolve in water for a long time, and is simple in preparation process, simple and convenient in process, low in production cost and suitable for large-scale production. 本发明涉及一种水溶性苯并噁嗪的合成方法，其包括如下步骤：以质量份计，将100份酚类化合物、30-2000份胺类化合物、10-150份甲醛、0-5份碱和100份有机溶剂混合，升温至85-100℃并恒温反应2-10h；恒温反应完成后，真空蒸馏至无液体蒸出，即得到水溶性苯并噁嗪。本发明方法解决了长期以来苯并噁嗪难以溶于水的技术难题，且制备工艺简单，工序简便，生产成本低廉，适宜规模化生产。